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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T14365 | AZ PFKFB3 26 | Glucokinase | |
AZ PFKFB3 26 is an effective and selective PFKFB3 inhibitor with an IC50 of 23 nM. The IC50s for PFKFB1 and PFKFB2 are 2.06 and 0.384 μM, respectively. | |||
T23552 | YZ9 | Glucokinase | |
PFKFB3 inhibitor | |||
T3105 | PFK-158 | Apoptosis , Glucokinase , Autophagy | |
PFK-158 is an effective and specific inhibitor PFKFB3. | |||
T2455 | PFK-015 | PFK15,PFK 015 | Glucokinase , Autophagy |
PFK-015 (PFK15) is an effective inhibitor of PFKFB3 (IC50: 110 nM) and inhibits PFKFB3 activity in Y cells (IC50: 20 nM). | |||
T67874 | PFKFB3-IN-2 | Glucokinase | |
PFKFB3-IN-2 is a 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 (PFKFB3) inhibitor. Anti-sense treatment against PFKFB3 was shown to reduce tumor growth rate in vivo. | |||
T3260 | (E)-3PO | 3PO | Glucokinase |
(E)-3PO is a PFKFB3 (6-phosphofructo-2-kinase/fructose-2, 6-bisphosphatase) inhibitor. | |||
T11741 | KAN0438757 | Glucokinase , Autophagy | |
KAN0438757 is a selective and potent inhibitor of the metabolic kinase PFKFB3 with an IC50 of 0.19 μM. | |||
T22223 | 3PO | Glucokinase , Autophagy | |
3PO is a small-molecule inhibitor of PFKFB3 (IC50: 22.9 μM), inhibiting the proliferation of several human malignant hematopoietic and adenocarcinoma cell lines (IC50: 1.4-24 μM). It suppresses glucose uptake, and decrea... | |||
T26346 | YN1 | YN-1,YN 1 | |
YN1 is an inhibitor of PFKFB3. | |||
T62894 | AZ-PFKFB3-67 quarterhydrate | ||
AZ-PFKFB3-67 quarterhydrate is a selective and potent inhibitor of the metabolic kinase PFKFB3 kinase, acting on PFKFB3 (IC50: 11 nM), PFKFB2 (IC50: 159 nM) and PFKFB1 (IC50: 1130 nM). | |||
T26730 | AZ-PFKFB3-67 | ||
AZ-PFKFB3-67 is a novel, potent and selective inhibitor of PFKFB3. | |||
T40565 | 5MPN | ||
5MPN is a novel compound that functions as a highly potent and selective inhibitor of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 (PFKFB4). This compound demonstrates oral activity and serves as a first-in-cla... |