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Search Results for " pfkfb3 inhibitor "

12

Compounds

Cat No. Product Name Synonyms Targets
T14365 AZ PFKFB3 26 Glucokinase
AZ PFKFB3 26 is an effective and selective PFKFB3 inhibitor with an IC50 of 23 nM. The IC50s for PFKFB1 and PFKFB2 are 2.06 and 0.384 μM, respectively.
T23552 YZ9 Glucokinase
PFKFB3 inhibitor
T3105 PFK-158 Apoptosis , Glucokinase , Autophagy
PFK-158 is an effective and specific inhibitor PFKFB3.
T2455 PFK-015 PFK15,PFK 015 Glucokinase , Autophagy
PFK-015 (PFK15) is an effective inhibitor of PFKFB3 (IC50: 110 nM) and inhibits PFKFB3 activity in Y cells (IC50: 20 nM).
T67874 PFKFB3-IN-2 Glucokinase
PFKFB3-IN-2 is a 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 (PFKFB3) inhibitor. Anti-sense treatment against PFKFB3 was shown to reduce tumor growth rate in vivo.
T3260 (E)-3PO 3PO Glucokinase
(E)-3PO is a PFKFB3 (6-phosphofructo-2-kinase/fructose-2, 6-bisphosphatase) inhibitor.
T11741 KAN0438757 Glucokinase , Autophagy
KAN0438757 is a selective and potent inhibitor of the metabolic kinase PFKFB3 with an IC50 of 0.19 μM.
T22223 3PO Glucokinase , Autophagy
3PO is a small-molecule inhibitor of PFKFB3 (IC50: 22.9 μM), inhibiting the proliferation of several human malignant hematopoietic and adenocarcinoma cell lines (IC50: 1.4-24 μM). It suppresses glucose uptake, and decrea...
T26346 YN1 YN-1,YN 1
YN1 is an inhibitor of PFKFB3.
T62894 AZ-PFKFB3-67 quarterhydrate
AZ-PFKFB3-67 quarterhydrate is a selective and potent inhibitor of the metabolic kinase PFKFB3 kinase, acting on PFKFB3 (IC50: 11 nM), PFKFB2 (IC50: 159 nM) and PFKFB1 (IC50: 1130 nM).
T26730 AZ-PFKFB3-67
AZ-PFKFB3-67 is a novel, potent and selective inhibitor of PFKFB3.
T40565 5MPN
5MPN is a novel compound that functions as a highly potent and selective inhibitor of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 (PFKFB4). This compound demonstrates oral activity and serves as a first-in-cla...
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